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1

Tetrazole analogues of cyclolinopeptide A: Synthesis, conformation, and biology

Krzysztof Kaczmarek, Stefan Jankowski, Ignacy Z. Siemion, Zbigniew Wieczorek, Ettore Benedetti, Paola Di Lello, Carla Isernia, Michele Saviano, Janusz Zabrocki

Journal:

Année:

2002

Langue:

english

Fichier:

PDF, 258 KB

english, 2002

2

Periodical changes of amino acid reactivity within the genetic code

Ignacy Z. Siemion, Piotr Stefanowicz

Journal:

Année:

1992

Langue:

english

Fichier:

PDF, 554 KB

english, 1992

3

Cyclopeptides of Linum usitatissimum

Bolesław Picur, Marek Cebrat, Janusz Zabrocki, Ignacy Z. Siemion

Journal:

Journal of Peptide Science

Année:

2006

Langue:

english

Fichier:

PDF, 106 KB

english, 2006

4

Sulfonated analogues of cyclolinopeptide A Synthesis, immunosuppressive activity and CD studies

MAREK CEBRAT, MAREK LISOWSKI, IGNACY Z. SIEMION, MICHAL ZIMECKI, ZBIGNIEW WIECZOREK

Journal:

Chemical Biology & Drug Design

Année:

1997

Langue:

english

Fichier:

PDF, 510 KB

english, 1997

5

Effects of cyclolinopeptide A on T lymphocyte activation and peptidyl prolyl isomerase activity

Gaymes, Terry J., Carrett, Neil J., Patel, Nishith, Kay, John E., Siemion, Ignacy Z.

Journal:

Biochemical Society Transactions

Année:

1996

Langue:

english

Fichier:

PDF, 110 KB

english, 1996

6

New hypothesis on amino acid complementarity and its evaluation on TGF-β2-related peptides

Ignacy Z. Siemion, Renata Zbozień-Pacamaj, Piotr Stefanowicz

Journal:

Journal of Molecular Recognition

Année:

2001

Langue:

english

Fichier:

PDF, 161 KB

english, 2001

7

Einfluß der Distanz des Prolincarbonyls vom β- und γ-Kohlenstoff auf die Lage der 13C-NMR-Signale

Prof. Dr. Ignacy Z. Siemion, Prof. Dr. Theodor Wieland, Dr. Karl-Heinz Pook

Journal:

Angewandte Chemie

Année:

1975

Fichier:

PDF, 285 KB

1975

8

Influence of the Distance of the Proline Carbonyl from the β and γ Carbon on the 13C Chemical Shifts

Prof. Dr. Ignacy Z. Siemion, Prof. Dr. Theodor Wieland, Dr. Karl-Heinz Pook

Journal:

Angewandte Chemie International Edition

Année:

1975

Langue:

english

Fichier:

PDF, 190 KB

english, 1975

9

Immunosuppressory activity of ubiquitin fragments containing retro-RGD sequence

Zbigniew Szewczuk, Piotr Stefanowicz, Andrzej Wilczyński, Anna Staszewska, Ignacy Z. Siemion, Michał Zimecki, Zbigniew Wieczorek

Journal:

Année:

2004

Langue:

english

Fichier:

PDF, 134 KB

english, 2004

10

Bioactive peptides: Conformational studies of [TYR4] cyclolinopeptide A

Michele Saviano, Filomena Rossi, Marta Filizola, Carla Isernia, Benedetto Di Blasio, Ettore Benedetti, Carlo Pedone, Ignacy Z. Siemion, Artur Pedyczak

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 591 KB

english, 1995

11

Die Konformation des Prolin-Ringes in Diketopiperazin-Systemen

Ignacy Z. Siemion

Journal:

European Journal of Organic Chemistry

Année:

1971

Fichier:

PDF, 363 KB

1971

12

Synthesis and biological activities of new analogues of thymopoietin II (32–36)

Eleonora Nawrocka-Bolewska, Ignacy Z. Siemion, Mirna Mihelić, Wolfgang Voelter

Journal:

European Journal of Organic Chemistry

Année:

1990

Langue:

english

Fichier:

PDF, 284 KB

english, 1990

13

NMR-Untersuchungen bei Prolin-enthaltenden Diketopiperazinen

Ignacy Z. Siemion

Journal:

Magnetic Resonance in Chemistry

Année:

1971

Fichier:

PDF, 271 KB

1971

14

Conformational investigations on cyclic dipeptides containing a proline residue by means of 13C n.m.r. spectroscopy

Ignacy Z. Siemion

Journal:

Magnetic Resonance in Chemistry

Année:

1976

Langue:

english

Fichier:

PDF, 382 KB

english, 1976

15

Enkephalin analogs modified in the aromatic ring of the N-terminal tyrosine residue

Wieslaw A. Kliś, Eleonora Nawrocka, Ignacy Z. Siemion, Andrzej Plech, Zdzisław Stachura, Zbigniew S. Herman

Journal:

Bioorganic Chemistry

Année:

1979

Langue:

english

Fichier:

PDF, 449 KB

english, 1979

16

Conformational preferences of the sequential fragments of the hinge region of the human IgA1 immunoglobulin molecule

Ignacy Z. Siemion, Artur Pedyczak, James Burton

Journal:

Biophysical Chemistry

Année:

1988

Langue:

english

Fichier:

PDF, 707 KB

english, 1988

17

The mean conformation of N-acetylamino acid N'-methylamides in dimethyl sulfoxide solution

Ignacy Z. Siemion, Bolestaw Picur

Journal:

Biophysical Chemistry

Année:

1988

Langue:

english

Fichier:

PDF, 567 KB

english, 1988

18

Conformational preferences of sequential fragments of the hinge region of human IgA1 immunoglobulin molecule: II

James Burton, Stephen G. Wood, Artur Pedyczak, Ignacy Z. Siemion

Journal:

Biophysical Chemistry

Année:

1989

Langue:

english

Fichier:

PDF, 509 KB

english, 1989

19

The regularity of changes of the Chou-Fasman parameters within the genetic code

Ignacy Z. Siemion

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 455 KB

english, 1994

20

Compositional frequencies of amino acids in the proteins and the genetic code

Ignacy Z. Siemion

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 349 KB

english, 1994

21

The informational context of the third base in amino acid codons

Ignacy Z. Siemion, Przemyslaw J. Siemion

Journal:

Année:

1994

Langue:

english

Fichier:

PDF, 711 KB

english, 1994

22

Chou-Fasman conformational amino acid parameters and the genetic code

Ignacy Z. Siemion, Przemysław J. Siemion, Krzysztof Krajewski

Journal:

Année:

1995

Langue:

english

Fichier:

PDF, 610 KB

english, 1995

23

The influence of the solvent on the amide conformation

Ignacy Z. Siemion

Journal:

Tetrahedron Letters

Année:

1966

Langue:

english

Fichier:

PDF, 203 KB

english, 1966

24

Stereoisomers of 4-amino-3-hydroxy-1-cyclohexanecarboxylic acid and 4-amino-3-oxo-1-cyclohexanecarboxylic acid as mimetics of a twisted cis-amide bond

Krzysztof Krajewski, Zbigniew Ciunik, Ignacy Z. Siemion

Journal:

Tetrahedron: Asymmetry

Année:

2001

Langue:

english

Fichier:

PDF, 179 KB

english, 2001

25

c-4-Amino-t-3-hydroxy-r-1-cyclohexanecarboxylic acid and cis-4-amino-3-oxo-1-cyclohexanecarboxylic acid—mimetics of dipeptides with a twisted cis-amide bond

Krzysztof Krajewski, Zbigniew Ciunik, Ignacy Z Siemion

Journal:

Tetrahedron: Asymmetry

Année:

1999

Langue:

english

Fichier:

PDF, 176 KB

english, 1999

26

The immunosuppressive mini-domain of human lactoferrin

Ignacy Z. Siemion, Jacek Sloń, Zbigniew Wieczorek

Journal:

Journal of Peptide Science

Année:

1995

Langue:

english

Fichier:

PDF, 491 KB

english, 1995

27

The Immunomodulatory Activity of Peptides Related to the DNA Contacting Loop of p53 Protein

Eleonora Bolewska-Pedyczak, Professor Ignacy Z. Siemion, Zbigniew Wieczorek

Journal:

Journal of Peptide Science

Année:

1996

Langue:

english

Fichier:

PDF, 470 KB

english, 1996

28

On the genetic and structural similarities between the squash seeds polypeptide trypsin inhibitors and wheat germ agglutinin

Ignacy Z. Siemion, Tadeusz Wilusz, Antoni Polanowski

Journal:

Molecular and Cellular Biochemistry

Année:

1984

Langue:

english

Fichier:

PDF, 157 KB

english, 1984

29

Tuftsin analogs and their biological activity

Ignacy Z. Siemion, Danuta Konopinska

Journal:

Molecular and Cellular Biochemistry

Année:

1981

Langue:

english

Fichier:

PDF, 725 KB

english, 1981

30

To the problem of biologically active conformation of enkephalin

Ignacy Z. Siemion, Zbigniew Szewczuk, Zbigniew S. Herman, Zdzislaw Stachura

Journal:

Molecular and Cellular Biochemistry

Année:

1981

Langue:

english

Fichier:

PDF, 413 KB

english, 1981

31

The new hypothesis on amino acid complementarity and its experimental proof

Piotr Stefanowicz, Renata Zbozień, Ignacy Z. Siemion

Journal:

International Journal of Peptide Research and Therapeutics

Année:

1998

Langue:

english

Fichier:

PDF, 193 KB

english, 1998

32

The problem of the biologically active conformation of thymopoietin

Ignacy Z. Siemion, Iwona Strug, Piotr Stefanowicz, Zbigniew Szewczuk

Journal:

International Journal of Peptide Research and Therapeutics

Année:

1998

Langue:

english

Fichier:

PDF, 206 KB

english, 1998

33

Stereochemistry of thiazolidine ring formation from aminals and cysteine

Aleksandra Wysłouch, Marek Lisowski, Artur Pȩdyczak, Ignacy Z. Siemion

Journal:

Tetrahedron: Asymmetry

Année:

1992

Langue:

english

Fichier:

PDF, 644 KB

english, 1992

34

The Problem of the Biologically Active Conformation of Thymopoietin

Ignacy Z. Siemion, Iwona Strug, Piotr Stefanowicz, Zbigniew Szewczuk

Journal:

International Journal of Peptide Research and Therapeutics

Année:

1998

Langue:

english

Fichier:

PDF, 87 KB

english, 1998

35

The New Hypothesis on Amino Acid Complementarity and its Experimental Proof

Piotr Stefanowicz, Renata Zbozień, Ignacy Z. Siemion

Journal:

International Journal of Peptide Research and Therapeutics

Année:

1998

Langue:

english

Fichier:

PDF, 32 KB

english, 1998

36

Conformation of model, alanine and proline containing tetrapeptides in water : Comparison of 13 C-n.m.r. and CD results

MAREK LISOWSKI, IGNACY Z. SIEMION, KATARZYNA SOBCZYK

Journal:

Chemical Biology & Drug Design

Année:

1983

Langue:

english

Fichier:

PDF, 361 KB

english, 1983

37

Comparison of conformational properties of proline and threonine residues

IGNACY Z. SIEMION, KATARZYNA SOBCZYK, MAREK LISOWSKI

Journal:

Chemical Biology & Drug Design

Année:

1986

Langue:

english

Fichier:

PDF, 651 KB

english, 1986

38

Conformational modification of the PRP-hexapeptide by a direct covalent attachment of aromatic side chain groups

ZBIGNIEW SZEWCZUK, ALEKSANDRA KUBIK, IGNACY Z. SIEMION, ZBIGNIEW WIECZOREK, KRYSTYNA SPIEGEL, MICHAL ZIMECKI, MARIA JANUSZ, JÓZEF LISOWSKI†

Journal:

Chemical Biology & Drug Design

Année:

1988

Langue:

english

Fichier:

PDF, 380 KB

english, 1988

39

Competition between tuftsin and HBV S-protein sequences

IGNACY Z. SIEMION, JACEK SŁON, ELEONORA NAWROCKA, ZBIGNIEW WIECZOREK

Journal:

Chemical Biology & Drug Design

Année:

1990

Langue:

english

Fichier:

PDF, 464 KB

english, 1990

40

Peptides related to the active fragment of “proline rich polypeptide”, an immunoregulatory protein of the ovine colostrums : Spectroscopic and computer modeling studies

IGNACY Z. SIEMION, GERD FOLKERS, ZBIGNIEW SZEWCZUK, ANDRZEJ JANKOWSKI, ALEKSANDRA KUBIK, WOLFGANG VOELTER

Journal:

Chemical Biology & Drug Design

Année:

1990

Langue:

english

Fichier:

PDF, 1.01 MB

english, 1990

41

Immunosuppressive analogues of hexapeptide Tyr-Val-Pro-Leu-Phe-Pro, an immune system stimulant

IGNACY Z. SIEMION, ALEKSANDRA KUBIK, MAREK LISOWSKI, ZBIGNIEW SZEWCZUK, MICHAL ZIMECKI, ZBIGNIEW WIECZOREK

Journal:

Chemical Biology & Drug Design

Année:

1991

Langue:

english

Fichier:

PDF, 642 KB

english, 1991

42

Suppression of tuftsin activity by the partial sequences of adenovirus type 2 proteins

IGNACY Z. SIEMION, JACEK J. SION, ZBIGNIEW WIECZOREK

Journal:

Chemical Biology & Drug Design

Année:

1993

Langue:

english

Fichier:

PDF, 564 KB

english, 1993

43

Does the edge-to-face interaction between aromatic rings occur in cyclolinopeptide A analogues?

IGNACY Z. SIEMION, MAREK CEBRAT, ANDRZEJ JANKOWSKI, MAREK LISOWSKI, ARTUR PFDYCZAK, ALEKSANDRA WYSLSOUCH

Journal:

Chemical Biology & Drug Design

Année:

1994

Langue:

english

Fichier:

PDF, 736 KB

english, 1994

44

The immunomodulatory diversity of the proteins of the transforming growth factor β (TGFβ) family

ZBIGNIEW WIECZOREK, JACEK SŁOń, ALICJA KLUCZYK, RENATA ZBOZIEń, PIOTR STAFANOWICZ, IGNACY Z. SIEMION

Journal:

Chemical Biology & Drug Design

Année:

1995

Langue:

english

Fichier:

PDF, 515 KB

english, 1995

45

Infrared Spectroscopic Investigations of Tuftsin and Its Analogs

Anna SUCHARDA-SOBCZYK, Ignacy Z. SIEMION, Danuta KONOPIŃSKA

Journal:

Année:

1979

Langue:

english

Fichier:

PDF, 752 KB

english, 1979

46

13C Nuclear Magnetic Resonance and Circular Dichroism Studies of the Tuftsin Conformation in Water

Ignacy Z. SIEMION, Marek LISOWSKI, Danuta KONOPIŃSKA, Eleonora NAWROCKA

Journal:

Année:

1980

Langue:

english

Fichier:

PDF, 465 KB

english, 1980

47

Analogs of RGDVY and GRGD peptides inhibit Mycobacterium kansasii phagocytosis

Ignacy Z. Siemion, Monika Gawłowska, Krzysztof Krajewski, Iwona Strug, Zbigniew Wieczorek

Journal:

Année:

2003

Langue:

english

Fichier:

PDF, 86 KB

english, 2003

48

The mimetics of antiadhesive peptides as the inhibitors of Mycibacterium kansasii phagocytosis

Ignacy Z. Siemion, Monika Gawłowska, Katarzyna Ślepokura, Monika Biernat, Zbigniew Wieczorek

Journal:

Année:

2005

Langue:

english

Fichier:

PDF, 135 KB

english, 2005

49

Cyclolinopeptide A (CLA) mediates its immunosuppressive activity through cyclophilin-dependent calcineurin inactivation

Terry J Gaymes, Marek Cebrat, Ignacy Z Siemion, John E Kay

Journal:

Année:

1997

Langue:

english

Fichier:

PDF, 488 KB

english, 1997

50

Immunological properties of the thymopentin-like fragments of HLA-DQ

Zbigniew Szewczuk, Ignacy Z. Siemion, Zbigniew Wieczorek

Journal:

Molecular Immunology

Année:

1996

Langue:

english

Fichier:

PDF, 818 KB

english, 1996